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Cover
Document and Entity Information
Financial Statements
Condensed Consolidated Balance Sheets
Condensed Consolidated Balance Sheets (Parenthetical)
Condensed Consolidated Statements of Comprehensive Loss
Condensed Consolidated Statements of Stockholders' Equity
Condensed Consolidated Statements of Cash Flows
Notes to Financial Statements
Operations and Basis of Presentation
Summary of Significant Accounting Policies
Acquisition of Icon Bioscience, Inc.
License and Collaboration Agreements
Intangible Assets
Accrued Expenses
Restructuring
Term Loan Agreement
Stockholders' Equity
Fair Value Measurements
Income Taxes
Commitments and Contingencies
Net Loss per Share
Subsequent Events
Accounting Policies
Summary of Significant Accounting Policies (Policies)
Notes Tables
Intangible Assets (Tables)
Accrued Expenses (Tables)
Restructuring (Tables)
Stockholders' Equity (Tables)
Fair Value Measurements (Tables)
Net Loss per Share (Tables)
Notes Details
Operations and Basis of Presentation - Additional Information (Detail)
Acquisition of Icon Bioscience, Inc - Additional Information (Detail)
License and Collaboration Agreements - Additional Information (Detail)
Intangible Assets - Reconciliation of Intangible Assets (Detail)
Intangible Assets - Additional Information (Detail)
Accrued Expenses - Schedule of Accrued Expenses (Detail)
Accrued Expenses - Additional Information (Detail)
Restructuring - Additional Information (Detail)
Restructuring - Summary of Reconciliation of Restructuring Costs (Detail)
Term Loan Agreement - Additional Information (Detail)
Stockholders' Equity - 2018 Equity Financing - Additional Information (Detail)
Stockholders' Equity - ATM Facility - Additional Information (Detail)
Stockholders' Equity - Summary of Reconciliation of Warrants to Purchase Share of the Company's Common Stock (Detail)
Stockholders' Equity - Warrants to Purchase Common Shares - Additional Information (Detail)
Stockholders' Equity - Equity Incentive Plans - Additional Information (Detail)
Stockholders' Equity - Stock Option Activity Under Plan (2016 Long-Term Incentive Plan) (Detail)
Stockholders' Equity - Stock Options - Additional Information (Detail)
Stockholders' Equity - Key Assumptions Used to Apply Option Pricing Model For Options Granted (2016 Long Term Incentive Plan) (Detail)
Stockholders' Equity - Time-Vested Restricted Stock Units - Additional Information (Detail)
Stockholders' Equity - Summary of Restricted Stock Unit Activity (Detail)
Stockholders' Equity - Performance-Based Stock Units - Additional Information (Detail)
Stockholders' Equity - Summary of Performance Stock Unit Activity (Detail)
Stockholders' Equity - Deferred Stock Units - Additional Information (Detail)
Stockholders' Equity - Inducement Option Grant - Additional Information (Detail)
Stockholders' Equity - Summary of Market-Based Restricted Stock Unit Activity (Detail)
Stockholders' Equity - Market-Based Restricted Stock Units - Additional Information (Detail)
Stockholders' Equity - Compensation Expense from Stock-Based Payment Awards (Detail)
Stockholders' Equity - Stock-Based Compensation Expense - Additional Information (Detail)
Fair Value Measurements - Assets and Liabilities Carried at Fair Value Measured on Recurring Basis (Detail)
Fair Value Measurements - Key Assumptions Used to Apply Option Pricing Model For Options Granted (Detail)
Fair Value Measurements - Summary of Changes in Fair Value of the Company's Derivative Liability (Detail)
Income Taxes - Additional Information (Detail)
Commitments and Contingencies - Additional Information (Detail)
Net Loss per Share - Potentially Dilutive Securities Excluded from Computation of Diluted Weighted-Average Shares (Detail)
Subsequent Events - Additional Information (Detail)
All Reports
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