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Cover
Document and Entity Information
Financial Statements
Condensed Consolidated Balance Sheets
Condensed Consolidated Balance Sheets (Parenthetical)
Condensed Consolidated Statements of Comprehensive Loss
Condensed Consolidated Statements of Stockholders' Equity
Condensed Consolidated Statements of Cash Flows
Notes to Financial Statements
Operations and Basis of Presentation
License and Collaboration Agreements
Intangible Assets
Fair Value Measurements
Accrued Expenses
Restructuring
Stockholders' Equity
Income Taxes
Commitments and Contingencies
Net Loss per Share
Notes Tables
Intangible Assets (Tables)
Fair Value Measurements (Tables)
Accrued Expenses (Tables)
Restructuring (Tables)
Stockholders' Equity (Tables)
Net Loss per Share (Tables)
Notes Details
Operations and Basis of Presentation - Additional Information (Detail)
License and Collaboration Agreements - Additional Information (Detail)
Intangible Assets - Reconciliation of Intangible Assets (Detail)
Intangible Assets - Additional Information (Detail)
Fair Value Measurements - Assets Carried at Fair Value Measured on Recurring Basis (Detail)
Accrued Expenses - Schedule of Accrued Expenses (Detail)
Accrued Expenses - Additional Information (Detail)
Restructuring - Additional Information (Detail)
Restructuring - Summary of Reconciliation of Restructuring Costs (Detail)
Stockholders' Equity - Additional Information (Detail)
Stockholders' Equity - Summary of Reconciliation of Warrants to Purchase Common Stock (Detail)
Stockholders' Equity - 2016 Long Term Incentive Plan - Additional Information (Detail)
Stockholders' Equity - Stock Option Activity Under Plan (2016 Long-Term Incentive Plan) (Detail)
Stockholders' Equity - Key Assumptions Used to Apply Option Pricing Model For Options Granted (2016 Long Term Incentive Plan) (Detail)
Stockholders' Equity - Time-Vested Restricted Stock Units - Additional Information (Detail)
Stockholders' Equity - Summary of Restricted Stock Unit Activity (Detail)
Stockholders' Equity - Performance-Based Stock Units - Additional Information (Detail)
Stockholders' Equity - Summary of Performance Stock Unit Activity (Detail)
Stockholders' Equity - Deferred Stock Units - Additional Information (Detail)
Stockholders' Equity - 2008 Incentive Plan - Additional Information (Detail)
Stockholders' Equity - Stock Option Activity Under Plan (Detail)
Stockholders' Equity - Inducement Option Grant - Additional Information (Detail)
Stockholders' Equity - Market-Based Restricted Stock Units - Additional Information (Detail)
Stockholders' Equity - Compensation Expense from Stock-Based Payment Awards (Detail)
Stockholders' Equity - Stock-Based Compensation Expense - Additional Information (Detail)
Income Taxes - Additional Information (Detail)
Commitments and Contingencies - Additional Information (Detail)
Net Loss per Share - Potentially Dilutive Securities Excluded from Computation of Diluted Weighted-Average Shares (Detail)
All Reports
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